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National News

Breast cancer is not known to respond well to treatments that harness the immune system

'Double-whammy' of chemo and immunotherapy could knock out deadly breast cancer

The scene after the helicopter crashed into a construction crane in Vauxhall, south London.

'Not one iota' of pressure put on helicopter pilot, says restaurant tycoon

Jeremy Hunt said patient safety 'has been my absolute priority throughout my tenure as Health Secretary'

Government set for Acas talks over strike threat by junior doctors

The years 2011 to 2015 have been the warmest five-year period on record

2015 set to be hottest year on record

The majority of excess deaths occurred in people aged 75 or over

Surge in winter deaths blamed on flu and vaccination issues

Police at Napier Street, Sheffield, after a body believed to be that of missing university student Caroline Everest was found in a river

Caroline Everest death: Man arrested on suspicion of rape

Poppi Worthington's father Paul Worthington leaves Liverpool Civil and Family Courts after a hearing into the death of the 13-month-old in December 2012.

'No real investigation' into 13-month-old Poppi Worthington's death

Experts have warned that the skies over Syria and Turkey are very crowded

Russia to deploy new anti-aircraft missile system to Syria amid Turkey tensions

Chancellor George Osborne leaves the Treasury ahead of his joint Autumn Statement and Spending Review

Chancellor George Osborne ditches tax credit cuts and protects police

The Government "skewed" the teaching of religion in schools by leaving out "non-religious world views", it is claimed

Humanists welcome ruling over new religious studies GCSE

The Bataclan theatre in Paris was targeted by terrorists

Eagles Of Death Metal drummer vows to finish Bataclan gig in Paris

Tim Yeo was the chairman of the Energy and Climate Change Select Committee

Tim Yeo evidence in libel action 'untrue and dishonest', says judge

A cow ended up stuck on a roof-top patio near Halifax

Fire crews rescue cow from roof-top patio

There were 143 births to girls aged 14 and under and 23,262 to those aged 15 to 19 in the last year

94 women aged 50 and over had babies last year - and 143 girls of 14 and under

The move followed a recent profit warning

UK Mail's Guy Buswell leaves after new profit warning

Thomas Cook posted profits after tax of £19 million - its first positive profit after tax since 2010

'Uncertain times' for Thomas Cook after wave of terror attacks

A house in Leicester which has been cordoned off for forensic examination as part of a police inquiry into the death of a 16-year-old

Boy, 16, dies after 'altercation between group of men' in Leicester

Lindsay Hoadley, of Summers Place Auctions in West Sussex, prepares a rare skeleton of a juvenile Allosaurus dinosaur

Rare dinosaur with 'cute factor' could fetch £500,000 at auction

Vehicles travel along the M1 motorway near Nottingahm

GPs should tell DVLA if drivers are not medically fit, says GMC

Babies born at weekends in NHS hospitals are more likely to be stillborn or die

Babies born at weekends in NHS hospitals 'more likely to be stillborn or die'

Jo Pavey with her gold medal after winning the 10000m final at the 2014 European Athletics Championships in Zurich

Athletes Jo Pavey and Wendy Sly to collect honours

Angelina Jolie announced in May 2013 that she had undergone a double mastectomy to reduce her chances of getting breast cancer

'Angelina effect' leads to rise in preventative double mastectomies

Sir David Attenborough will be interviewed by Kirsty Young

BBC programme to celebrate Sir David Attenborough's 90th birthday

Her Majesty's Courts and Tribunal Service said 217 incidents of 'aggressive contact/assault' were recorded in court and tribunal buildings last year

Aggressive incidents in court buildings on the increase

Five people have been arrested in the TalkTalk cyber attack investigation

TalkTalk cyber attack probe: Fifth person arrested

The union said more than 500 jobs will be affected by the office closures

Open University staff press ahead with strike as centre closure plans firmed up

Protesters gathered at Colnbrook immigration removal centre

Activists 'glue themselves to immigration centre gate' in deportation protest

Ferne McCann won plaudits for her bravery

Ferne McCann in tears during I'm A Celebrity Bushtucker Trial

Teenagers find it more difficult to multitask, a study has concluded

Adults 'better than teenagers at multitasking'

Climate change could lead to more droughts in Africa

Funding boost to help Africa cope with climate change

Babies born at weekends in NHS hospitals are more likely to be stillborn or die

Babies born at weekends in NHS hospitals 'more likely to be stillborn or die'

Sir David Attenborough will be interviewed by Kirsty Young

BBC programme to celebrate Sir David Attenborough's 90th birthday

Abid Naseer plotted to bomb Manchester's Arndale Centre (Greater Manchester Police/PA)

40-year US jail term for man who plotted to bomb Manchester's Arndale Centre

The Duke of Cambridge meets Tusk Conservation Awards finalists

William helps honour 'unsung heroes' of conservation at Tusk awards

EasyJet will not fly to Sharm el-Sheikh until January 6 and BA said its flights will be suspended until January 14

British Airways and easyJet suspend Sharm el-Sheikh flights until new year

Police chiefs are warning that budget cuts will hamper the ability to tackle a terrorist threat

Government warned that police cuts would hamper terrorism fight

A Middle East expert has warned that the skies over Syria and Turkey are an "incredibly crowded air space"

David Cameron urges 'communication' after Turkish fighter downs Russian warplane

Police examine the scene in Napier Street, Sheffield, where a body was found

Police comb river bank after body found in hunt for student Caroline Everest

George Osborne has confirmed that his Spending Review will allocate an extra £3.8 billion to the NHS in 2016-17

'Risks remain' despite George Osborne's £3.8bn cash boost for NHS

The Labour leader is known to be a strong opponent of nuclear weapons

20 Labour MPs defy Jeremy Corbyn over Trident debate

Lady Colin Campbell had to do the camp's laundry

No more Bushtucker Trials, please, says I'm A Celebrity's Lady C

Tesco drivers will be balloted on pre-Christmas strike action

Tesco delivery staff to vote on festive period strikes over pay

Police launched a murder investigation after the stabbing in Holloway

Brother's tribute to 'lovely' teenager stabbed to death in Holloway

The advert features the Lord's Prayer being recited

Lord's Prayer cinema advert ban agency defends policy as 'correct and fair'

Some 14.7 million shoppers will take part in the sales bonanza from this Friday

Black Friday 2015: Britons expected to spend £3.49bn over four days

The Smiler ride will reopen next year

Human error blamed for Smiler rollercoaster crash at Alton Towers

David Cameron has described dementia as one of the greatest enemies of humanity

Campaigners hail Government pledge for new £150m dementia research institute

Andy Murray has praised the British Davis Cup side's security team

Andy Murray understands Davis Cup travel security fears

Passengers on the Newcastle Metro system rallied to the defence of Muslim women who were subjected to a hateful tirade

Woman thanks passengers for support as police seek man over anti-Muslim rant

The CBI said 38% of retail firms had seen an increase in sales compared to the same period a year ago, while 31% had seen a drop-off

Retail sales slow as shoppers hold out for Black Friday

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